Related Experiment Videos
[Evidence-based, best-practice guidelines for primary prevention of osteoporosis and osteoporotic fractures]
1Department of Public Health, Kinki University School of Medicine, Japan.
Abstract:
Community health interventions aimed at increasing peak bone mass and decreasing lifelong bone loss could substantially reduce the incidence of osteoporosis and osteoporotic fractures. Before now, no evidence-based practice guidelines for primary prevention of osteoporosis and osteoporotic fractures have been produced for public health center workers, primary care providers, and community health specialists. We constructed guidelines that present the effects of life-style factors, such as food and nutritional intake, in (1) increasing peak bone mass among young adults, (2) minimizing bone loss among menopausal and postmenopausal women, and (3) preventing fractures among the elderly. To do this, we systematically reviewed relevant evidence on the effects of physique, milk, dairy products, vitamin K, vitamin C, vitamin A, magnesium, and isoflavones. The guidelines provide optimum intake values and recommendations for young adults, women, and the elderly.
Related Concept Videos
Osteoclasts in Bone Remodeling
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Cancer Prevention
Some...
Essential Minerals for Bone Health
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
Levels of Health Promotion and Illness Prevention
In primary prevention, actions taken before disease onset prevent the disease from...