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12q13 abnormality in rhabdomyosarcoma. A nonrandom occurrence?
P Roberts1, C F Browne, I J Lewis
1Regional Cytogenetics Unit, St. James's University Hospital, Leeds, United Kingdom.
Cancer Genetics and Cytogenetics
|June 1, 1992
Abstract:
We describe two cases of rhabdomyosarcoma with a translocation involving 12q13 as the primary cytogenetic abnormality. Literature review of 35 cases has identified 3 other cases with this abnormality, and we speculate that this may be another nonrandom rearrangement in rhabdomyosarcoma.