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Eruptive lichen planus.

T Kanzaki1, N Otake, M Nagai

  • 1Department of Dermatology, Nagoya City University Medical School, Japan.

The Journal of Dermatology
|April 1, 1992
PubMed
Summary
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A rare, intensely itchy skin condition, acute eruptive lichen planus, presented with over ten thousand lesions. Oral etretinate demonstrated a dramatic treatment response after other therapies failed.

Area of Science:

  • Dermatology
  • Clinical Case Reports
  • Rare Skin Diseases

Background:

  • Lichen planus is an inflammatory condition affecting skin and mucous membranes.
  • Acute eruptive lichen planus is a rare, rapidly progressing variant.
  • This case highlights a unique presentation and treatment challenge.

Observation:

  • A 51-year-old male presented with a rapidly spreading, intensely pruritic eruption.
  • The patient developed over ten thousand papulosquamous lesions on his extremities and trunk within months.
  • Initial treatments with topical steroids, cyclosporine, and griseofulvin were ineffective.

Findings:

  • The case describes a rare variety of acute eruptive lichen planus.
  • A dramatic and positive response was observed with oral etretinate treatment.

Related Experiment Videos

  • This suggests etretinate as a potential therapeutic option for severe, treatment-resistant cases.

    • Implications:

    • This case highlights the potential of oral etretinate in managing rare and severe forms of lichen planus.
    • Further research may explore etretinate's role in similar dermatological conditions.
    • Clinicians should consider etretinate for patients with refractory acute eruptive lichen planus.