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Retinal nerve fiber layer thickness in optic tract syndrome
Yasuko Tatsumi1, Akiyasu Kanamori, Azusa Kusuhara
1Department of Organ Therapeutics, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Japanese Journal of Ophthalmology
|August 3, 2005
Summary
Optic tract syndrome (OTS) causes vision loss and optic nerve damage. Optical coherence tomography (OCT) quantifies retinal nerve fiber layer thickness (RNFLT) reduction in OTS patients, aiding diagnosis.
Area of Science:
- Ophthalmology
- Neurology
- Medical Imaging
Background:
- Optic tract syndrome (OTS) presents with incongruous homonymous hemianopia and optic atrophy.
- Quantitative assessment of retinal nerve fiber layer thickness (RNFLT) in OTS is not well-established.
Observation:
- A case study involving a 20-year-old woman with blunt head trauma revealed a relative afferent pupillary defect and homonymous hemianopia.
- Optical coherence tomography (OCT) was used to measure RNFLT 31 months post-trauma.
Findings:
- Significant RNFLT reduction was observed in all quadrants, particularly in the nasal and temporal quadrants of the left eye and the inferior quadrant of the right eye.
- Reductions in RNFLT exceeded three standard deviations from normal in specific quadrants, correlating with optic atrophy patterns.
Implications:
- OCT provides quantitative data on RNFLT reduction in OTS.
- This quantitative assessment aids in diagnosing and understanding the visual field defects associated with optic tract lesions.