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Microbial transformation of mestranol by Cunninghamella elegans

Muhammad Iqbal Choudhary1, Syed Ghulam Musharraf, Zafar Ali Siddiqui

  • 1International Center for Chemical Sciences, H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. hej@cyber.net.pk

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Transformation

Microbial communities are dynamic environments where cell lysis releases free DNA into the surroundings. Other cells can take up this extracellular DNA through a process known as transformation.When a cell incorporates this foreign DNA into its genome, resulting in genetic modification, the process is known as transformation. Cells capable of this process are termed competent. Competence can be natural, as observed in certain bacteria and archaea, or artificially induced in the...