[Effects of anesthesia on the metabolic response during pelvic surgery]

Dividing anesthesia for gynecological laparotomy into nitrous oxide-oxygen-halothane (GOF) anesthesia (group A), nitrous oxide-oxygen (GO) plus ketamine anesthesia (group B) and GOF plus epidural anesthesia (group C), we studied effects of each anesthesia on circulatory and metabolic systems. During the operation, influence on the heart rate was slight in three groups, while systolic pressure decreased significantly in group C. The lactic acid in the blood was elevated in three groups, but the elevation was least in group C. The elevation of lactic acid pyruvic acid ratio (L/P) was less in group C. The blood glucose level was elevated significantly in three groups, and it was highest in group A. On the other hand NEFA was elevated significantly in group A, while no change was noted in group B, and decreasing was noted in group C. The results indicate that no large influence of each anesthesia on the metabolic system was noted in group A and B, and its influence was the least in group C.