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Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
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Proteomics in the forefront of cancer biomarker discovery

Sudhir Srivastava1, Rashmi-Gopal Srivastava

  • 1Cancer Biomarkers Research Group of National Cancer Institute, EPN 3142, 6130 Executive Boulevard, Rockville, MD 20852, USA. srivasts@mail.nih.gov

Journal of Proteome Research
|August 9, 2005
PubMed
Abstract

No abstract available in PubMed .

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
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Targeted Cancer Therapies02:57

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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