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Updated: Aug 16, 2026

Monocular Visual Deprivation and Ocular Dominance Plasticity Measurement in the Mouse Primary Visual Cortex
Published on: February 8, 2020
Greater losses in sensitivity to second-order local motion than to first-order local motion after early visual
D Ellemberg1, T L Lewis, N Defina
1Département de Kinésiologie, Université de Montréal, Montréal, Qué., Canada. dave.ellemberg@umontreal.ca
Abstract:
We compared sensitivity to first-order versus second-order local motion in patients treated for dense central congenital cataracts in one or both eyes. Amplitude modulation thresholds were measured for discriminating the direction of motion of luminance-modulated (first-order) and contrast modulated (second-order) horizontal sine-wave gratings. Early visual deprivation, whether monocular or binocular, caused losses in sensitivity to both first- and second-order motion, with greater losses for second-order motion than for first-order motion. These findings are consistent with the hypothesis that the two types of motion are processed by different mechanisms and suggest that those mechanisms are differentially sensitive to early visual input.
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