Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple-quantum vector field imaging by magnetic resonance.

Louis-S Bouchard1, Warren S Warren

  • 1Department of Chemistry, Princeton University, NJ 08544, USA. LSBouchard@waugh.cchem.berkeley.edu

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|August 10, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficient <sup>15</sup>N hyperpolarization of [<sup>15</sup>N<sub>3</sub>]metronidazole antibiotic via spin-relayed pulsed SABRE-SHEATH.

Journal of magnetic resonance open·2026
Same author

Quantitative Assessment of Brain Glucose Metabolism Using Dynamic Glucose-Enhanced Magnetic Resonance Fingerprinting (DGE-MRF).

Chemical & biomedical imaging·2026
Same author

Weak solutions to the Bloch equations with distant dipolar field.

The Journal of chemical physics·2026
Same author

Multi-tissue transcriptomic aging atlas reveals predictive aging biomarkers in the killifish.

Nature aging·2026
Same author

Angle-resolved Measurements Reveal the Origin of Signal Anisotropy in Pump-probe Microscopy.

bioRxiv : the preprint server for biology·2026
Same author

Admissibility of solitary wave modes in long-runout debris flows.

Physical review. E·2025
Same journal

Localization-driven exchange contrast in diffusion exchange spectroscopy.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

4.5 Tesla superconducting miniature magnet in liquid nitrogen.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Folding and unfolding dynamics of a DNA aptamer studied by heteronuclear <sup>1</sup>H-<sup>13</sup>C correlation zz-exchange spectroscopy.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Multi-spin control from one-spin pulses.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Altering MRI rotating frame relaxations by changing the truncation level of Hyperbolic Secant pulse.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
Same journal

Effects of proton exchange on the lifetimes of long-lived states in aliphatic chains.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2026
See all related articles

We developed a new method to map fiber orientation in tissues and materials non-invasively. This technique uses intermolecular multiple-quantum coherences to reveal structural details beyond conventional MRI capabilities.

Area of Science:

  • Physics
  • Materials Science
  • Biophysics

Background:

  • Mapping fiber orientation is crucial for understanding material properties and biological tissue structure.
  • Conventional Magnetic Resonance Imaging (MRI) and diffusion tensor imaging have limitations in probing certain length scales and complex structures.

Purpose of the Study:

  • To introduce a novel non-invasive method for determining fiber orientation in anisotropic materials and biological tissues.
  • To demonstrate the capability of this technique to probe micro-scale structural information.

Main Methods:

  • Utilizing intermolecular multiple-quantum coherences (IMQCs) to probe nuclear magnetic dipole interactions of water molecules.
  • Employing a CRAZED (CArrYing multiple quantum coherences with ZEro echo delay) sequence to encode spatial distributions.

Related Experiment Videos

  • Acquiring signals with linear magnetic field gradients along X, Y, and Z axes to determine spherical coordinates (theta, phi) of fiber orientation.

    • Main Results:

    • Established an empirical relationship between signal intensity differences and the polar (theta) and azimuthal (phi) angles of fiber orientation.
    • Demonstrated that signal subtractions (e.g., ||G(Z)|| - ||G(X)|| - ||G(Y)||) are zero for isotropic materials and non-zero for anisotropic materials.
    • Experimental validation in structured media confirmed the technique's sensitivity to structural anisotropy.

    Conclusions:

    • The developed IMQC-based method provides a non-invasive approach to map fiber orientation.
    • This technique offers superior resolution for probing micro-scale structures compared to conventional MRI and DTI.
    • Potential applications in materials science and biomedical imaging for detailed structural analysis.