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Mesenteric venulitis in a 71-year-old man after acute appendicitis
1Orlando Regional Healthcare, Orlando, Florida, USA.
The American Surgeon
|August 11, 2005
Summary
Mesenteric inflammatory veno-occlusive disease (MIVOD) is a rare cause of intestinal ischemia. This case report details a patient experiencing MIVOD post-appendectomy, highlighting its necrotizing venulitis and self-limiting nature post-resection.
Area of Science:
- Gastroenterology
- Pathology
- Vascular Surgery
Background:
- Mesenteric inflammatory veno-occlusive disease (MIVOD) is a recently identified clinicopathological entity.
- It presents as intestinal ischemia of unknown origin, characterized by venulitis with specific morphological features.
Observation:
- A 71-year-old male developed focal intestinal ischemia post-laparoscopic appendectomy.
- Surgical re-exploration revealed a 20-cm segment of ischemic jejunum requiring resection.
Findings:
- Histopathological examination of the resected jejunum showed early ischemic mucosal injury.
- Necrotizing mesenteric venulitis with thrombosis, consistent with MIVOD, was identified.
Implications:
- This case adds to the understanding of MIVOD, a rare vasculitis.
- The findings suggest MIVOD may be self-limiting, resolving after surgical intervention.
- Further research into the unknown etiology of MIVOD is warranted.