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Behavioral Characterization of Pentylenetetrazole-induced Seizures: Moving Beyond the Racine Scale
Published on: July 8, 2025
Case of symptomatic propriospinal myoclonus evolving toward acute "myoclonic status"
Mauro Manconi1, Barbara Sferrazza, Sandro Iannaccone
1Department of Neurology, Vita-Salute University, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele-Turro, Milan, Italy. manconi.mauro@hsr.it
Abstract:
Propriospinal myoclonus is a rare motor disorder consisting of involuntary spinal-generated muscular jerks. Here, we report a severe and uncommon case of propriospinal myoclonus that appeared after a vertebral fracture of T11. In this patient, the polysomnographic investigation showed continuing focal myoclonic activity in axial muscles during stable sleep and an acute progression into a myoclonic "status" associated with respiratory failure and loss of consciousness. It is necessary to consider this severe progression and support it with prompt emergency maneuvers and adequate pharmacotherapy.
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