Related Experiment Video
Updated: Aug 16, 2026

05:39
Non-Intubated Video-Assisted Thoracoscopic Surgery
Published on: May 26, 2023
Ventilatory and hemodynamic changes during retroperitoneal and transperitoneal laparoscopic nephrectomy: a
Andrei Nadu1, Perla Ekstein, Amir Szold
1Department of Urology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
The Journal of Urology
|August 12, 2005
Summary
The retroperitoneal laparoscopic approach for nephrectomy causes less disruption to breathing and circulation compared to the transperitoneal method. This makes it a potentially safer option for patients undergoing kidney removal surgery.
Area of Science:
- Urology
- Anesthesiology
- Surgical Techniques
Background:
- Laparoscopic nephrectomy is commonly performed using either transperitoneal or retroperitoneal approaches.
- Both methods have distinct impacts on patient physiology during surgery.
Purpose of the Study:
- To compare the ventilatory and hemodynamic effects of transperitoneal versus retroperitoneal laparoscopic nephrectomy.
Main Methods:
- Prospective study comparing 24 retroperitoneal and 15 transperitoneal laparoscopic nephrectomies.
- Patients initially ventilated in volume-controlled mode; changes to pressure-controlled ventilation were made based on specific physiological parameters.
Main Results:
- Transperitoneal approach led to significantly higher peak inspiratory and plateau pressures (approx. 30% increase) compared to retroperitoneal.
- Ventilatory mode changes were required in 8 transperitoneal cases, none in retroperitoneal.
- Hemodynamic changes (heart rate, blood pressure) were approximately 13% greater with the transperitoneal approach.
Conclusions:
- The retroperitoneal laparoscopic approach for nephrectomy results in less interference with ventilatory and hemodynamic functions.
- This suggests the retroperitoneal approach may offer a more stable physiological environment during laparoscopic kidney surgery.

