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Updated: Aug 16, 2026

An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
Risk factors for mortality in children with candidemia
Theoklis E Zaoutis1, Susan E Coffin, Jaclyn H Chu
1Division of Infectious Diseases, The Children's Hospital of Philadelphia, PA 19104, USA. zaoutis@email.chop.edu
Abstract:
We performed a retrospective cohort study of hospitalized children with positive blood cultures for Candida species. Independent risk factors for mortality by multivariable analysis were location in the pediatric intensive care unit at the time of infection (hazard ratio, 6.3; 95% confidence interval, 1.6-24.3) and the presence of an arterial catheter (hazard ratio, 2.4; 95% confidence interval, 1.1-5.8). Our findings help identify a group of pediatric patients that should be targeted for future interventions to prevent and treat candidemia.
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