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Giant appendiceal mucocele: report of a case and brief review
Bernardino Rampone1, Franco Roviello, Daniele Marrelli
1Department of General Surgery and Surgical Oncology, University of Siena, Italy.
Abstract:
Mucocele of the appendix is a rare lesion, characterized by distension of the lumen due to accumulation of mucoid substance. This disease is often asymptomatic and pre-operative diagnosis is rare. If untreated, one type of mucocele may rupture producing a potentially fatal entity known as pseudomyxoma peritonei. The type of surgical treatment is related to the dimensions and to histology of the mucocele. Appendectomy is used for simple mucocele or for cystadenoma. Right hemi-colectomy is recommended for cystadenocarcinoma. In this paper, we report a case of a 51-year-old woman with a mobile, painless mass in the right lower quadrant of abdomen caused by a giant appendiceal mucocele. Imaging showed a large, tubular, cystic structure extending below from the inferior wall of the cecum. Surgery revealed a giant retro-cecal appendix measuring 17 cm in length and 4 cm in diameter. The final pathologic diagnosis was mucocele caused by mucinous cystadenoma.
Insights
Giant appendiceal mucocele, a rare condition, can be asymptomatic and challenging to diagnose pre-operatively. This case highlights a large mucocele diagnosed via imaging and confirmed by pathology, emphasizing surgical considerations.
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Mucocele of the appendix is a rare appendiceal lesion characterized by lumen distension with mucoid substance.
- Often asymptomatic, pre-operative diagnosis of appendiceal mucocele is infrequent.
- Rupture can lead to pseudomyxoma peritonei, a potentially fatal condition.
Observation:
- A 51-year-old woman presented with a mobile, painless right lower quadrant abdominal mass.
- Imaging revealed a large, tubular, cystic structure extending from the cecum.
- Surgery identified a giant, retro-cecal appendix measuring 17 cm in length and 4 cm in diameter.
Findings:
- The final pathological diagnosis was mucocele of the appendix.
- The mucocele was caused by a mucinous cystadenoma.
- Surgical treatment decisions for appendiceal mucocele depend on size and histology.
Implications:
- This case underscores the importance of considering appendiceal mucocele in the differential diagnosis of abdominal masses.
- Appropriate surgical intervention, such as appendectomy or hemi-colectomy, is crucial for managing appendiceal mucocele based on its characteristics.
- Early diagnosis and treatment can prevent complications like pseudomyxoma peritonei.
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