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In Vivo Imaging and Tracking of Technetium-99m Labeled Bone Marrow Mesenchymal Stem Cells in Equine Tendinopathy

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Hemangiosarcoma in 11 young horses.

Imogen Johns¹, Jennifer O Stephen, Fabio Del Piero

¹University of Pennsylvania, George D. Widener Hospital, New Bolton Center, Kennett Square, PA 19348, USA.

Journal of Veterinary Internal Medicine

|August 13, 2005

Summary

This study examined hemangiosarcoma in young horses (<= 3 years). Early diagnosis and surgical resection offer the best chance for cure, though some cases may resolve spontaneously.

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Area of Science:

Veterinary Oncology
Equine Neoplasia

Background:

Hemangiosarcoma is a rare cancer in horses.
Young horses may present unique clinical characteristics for this neoplasm.

Purpose of the Study:

To characterize hemangiosarcoma in horses aged 3 years or younger.
To identify clinical and diagnostic features of this rare condition in young equines.

Main Methods:

Retrospective review of medical records (1982-2004) for horses <= 3 years with histopathologic diagnosis of hemangiosarcoma.
Analysis of clinical presentation, physical examination findings, laboratory results, and diagnostic imaging.

Main Results:

Eleven cases were identified, predominantly Thoroughbreds.
Common presentations included cutaneous/leg swellings or joint effusion, with signs of tachycardia, fever, and depression.
Laboratory findings included anemia, hyper/hypofibrinogenemia, thrombocytopenia, and neutrophilic leukocytosis.
Diagnostic imaging was not definitive; early histopathologic diagnosis was crucial.

Conclusions:

Early histopathologic diagnosis is vital for potential cure through surgical resection of localized masses.
Spontaneous resolution occurred in two cases.
Observation may be warranted for medically stable horses with non-interfering masses.