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Successful renal transplantation during pregnancy
Phoebe M Hold1, Christopher F Wong, Raman K Dhanda
1The Transplant Unit, Royal Liverpool University Hospital, Liverpool, UK. fibhold@aol.com
Summary
Pregnancy following a kidney transplant can have a successful outcome. This case study highlights a healthy mother and baby after a renal transplant during early pregnancy.
Area of Science:
- Nephrology
- Transplantation
- Obstetrics
Background:
- Limited data exists on renal transplantation during pregnancy.
- Chronic kidney disease (CKD) necessitates renal replacement therapy, including transplantation.
- Pregnancy in women with CKD poses significant risks.
Observation:
- A 23-year-old woman with CKD underwent a live-related renal transplant.
- Pregnancy was incidentally discovered at 13 weeks gestation, 5 days post-transplant.
- The patient received ciclosporin monotherapy and valacyclovir prophylaxis.
Findings:
- Stable renal function was maintained throughout the pregnancy.
- The pregnancy progressed normally without complications.
- A healthy male infant was delivered vaginally at 37 weeks gestation.
Implications:
- Renal transplantation during pregnancy can achieve successful maternal and fetal outcomes.
- This case supports the feasibility of managing pregnancy post-renal transplant.
- Further research is warranted to establish optimal protocols for this patient population.