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Updated: Aug 16, 2026

Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
[Familial small-vessel vasculitis of the kidney]
J P Devaux1, X Kyndt, R Binaut
1Service de Medecine Internenéphrologie, Centre Hospitalier de Valenciennes.
Introduction:
Familial forms of small-vessel vasculitis has been reported in 14 families (including this one).
Cases:
A father and son were both diagnosed with renal vasculitis (pauci-immune crescentic glomerulonephritis). Both had antimyeloperoxidase autoantibodies, and there was no evidence of a common environmental factor.
Discussion:
These cases suggest the role of constitutional factors in the pathogenesis of antineutrophil cytoplasmic antibody-associated vasculitis.
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