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[Age, an independent risk factor for thrombosis. Epidemiologic data]
I Mahé1, C Caulin, J F Bergmann
1Service de Médecine A, Hôpital Lariboisière, Paris (75). isabelle.mahe@lrb.ap-hop-paris.fr
Insights
The risk of arterial and venous thrombosis significantly increases with age, particularly in individuals over 80. Early identification of risk factors is crucial for preventing thrombotic events in the elderly.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Hematology
Context:
- Thrombosis incidence, both arterial and venous, escalates with advancing age.
- Elderly populations exhibit a higher prevalence of conditions predisposing to thrombosis, such as atheromatous diseases and atrial fibrillation.
- Ischemic heart disease is a leading cause of mortality in older adults.
Purpose:
- To highlight the age-related increase in thrombotic event risk.
- To emphasize the significance of atrial fibrillation as a risk factor for cerebrovascular accidents in the elderly.
- To underscore the rising incidence of venous thromboembolic disease with age.
Summary:
- The incidence of arterial and venous thrombosis rises with age, with conditions like atrial fibrillation and venous thromboembolic disease becoming more prevalent.
- Atrial fibrillation affects approximately 10% of individuals over 80, increasing stroke risk.
- Venous thromboembolic disease incidence rises significantly in those over 75.
- Elderly individuals frequently possess multiple risk factors, amplifying their thrombotic event risk.
Impact:
- Recognizing the heightened risk of thrombosis in the elderly necessitates systematic screening for acquired risk factors.
- Proactive assessment and management of risk factors are essential for effective prevention strategies in geriatric populations.
- This understanding supports targeted interventions to mitigate the burden of thrombotic diseases in aging societies.
Abstract:
The incidence of thrombosis--arterial and venous--increases with age. This is the case for atheromatous diseases, atrial fibrillation and even venous thromboembolic disease. Ischemic heart disease is the most common cause of death in the elderly. Atrial fibrillation, an independent risk factor for cerebral vascular accidents, affects around 10% of persons older than 80 years. The incidence of venous thromboembolic disease increases with age, reaching 12.5 per 1000 people older than 75 years, compared with 5 per 1000 aged 60-75 and 2.5 per 1000 aged 40-59. Elderly persons often have two or more cardiovascular or venous thromboembolic risk factors and thus a still higher risk of thrombotic events. Their risk of thrombosis justifies the systematic search for acquired risk factors to assess the level of risk and take appropriate prevention measures.
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