Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Apoptosis: a basic physiologic process in wound healing.

Nirendra K Rai1, Kamlakar Tripathi, Deborshi Sharma

  • 1Department of General Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

The International Journal of Lower Extremity Wounds
|August 16, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness and Safety of Saroglitazar in Patients With Metabolic Disease in India Stratified by Estimated Glomerular Filtration Rate (eGFR): A Retrospective, Observational, Electronic Medical Record (EMR)-Based Real-World Evidence Study.

Cureus·2026
Same author

Hypertension Management Beyond Blood Pressure Control in India: An Expert Consensus on Angiotensin II Receptor Blocker and Calcium Channel Blocker Combination Therapy With Reference to Telmisartan and Cilnidipine.

Cureus·2026
Same author

Effect of Single Perineural Injection of Platelet Rich Plasma on Nerve Function in Hansen's Disease With Truncal Neuropathy: An Interventional Study.

Cureus·2026
Same author

Sleep hygiene practices and its impact on sleep quality and mood.

Journal of family medicine and primary care·2025
Same author

Human long non-coding RNAs acquired from bacteria via horizontal gene transfer promote gallbladder cancer.

Molecular biology reports·2025
Same author

Is cross-species horizontal gene transfer responsible for gallbladder carcinogenesis.

World journal of surgical oncology·2024
Same journal

Genetic Evidence for Adiposity-Related Susceptibility and Heel BMD-Proxied Skeletal Resilience in Charcot Foot: A Two-Sample Mendelian Randomization Study.

The international journal of lower extremity wounds·2026
Same journal

Metabolic Intensification in Limb Salvage: A Doubly Robust Dual-Center Study Establishing 37.9 g/L as the Physiological Requirement for Diabetic Foot Ulcer Regeneration.

The international journal of lower extremity wounds·2026
Same journal

Efficacy and Safety of Kangfuxin Liquid Adjuvant Therapy Versus Standard Dressing in Treating Stage II-III Pressure Ulcers: A Meta-Analysis of Randomized Controlled Trials.

The international journal of lower extremity wounds·2026
Same journal

Revealing the Association Between Dietary Quality index and Diabetic Foot Ulcer: A Case-Control Study.

The international journal of lower extremity wounds·2026
Same journal

SGLT-2 Inhibitors and Lower-limb Amputations in Diabetes: A Misunderstood Relationship? Insights from a Retrospective Study.

The international journal of lower extremity wounds·2026
Same journal

Comparison of Safe Laser 1800 Infra and Standard Treatment for Chronic Non-Healing Wounds.

The international journal of lower extremity wounds·2026
See all related articles

Programmed cell death (apoptosis) is crucial for wound repair. In diabetic foot wounds, hyperglycemia disrupts apoptosis, leading to delayed healing and contributing to disease progression.

Area of Science:

  • Cell Biology
  • Biochemistry
  • Pathology

Background:

  • Apoptosis, or programmed cell death, is a vital cellular process.
  • Dysregulation of apoptosis is implicated in various diseases.
  • Apoptosis plays a critical role in the normal wound repair process.

Purpose of the Study:

  • To examine the role of apoptosis in the development of diabetic foot wounds.
  • To propose that deregulated apoptosis contributes to delayed healing in diabetic wounds.

Main Methods:

  • Literature review and analysis of existing research on apoptosis and diabetic wound healing.

Main Results:

  • Hyperglycemia deregulates sequential apoptotic events through multiple mechanisms.

Related Experiment Videos

  • Deregulated apoptosis is a significant factor in delayed wound healing, particularly in diabetic patients.

    • Conclusions:

    • Apoptosis is essential for effective wound repair.
    • Disrupted apoptosis due to hyperglycemia is a key mechanism underlying diabetic foot wound chronicity.