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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

Clinical factors associated with persistent pericardial effusion after successful primary coronary angioplasty

Tetsuro Sugiura1, Seishi Nakamura, Yoshihiro Kudo

  • 1Department of Laboratory Medicine, Kochi Medical School, Kohasu Oko-cho Nankoku City, Kochi, Japan 783-8505. sugiurat@med.kochi-u.ac.jp

Chest
|August 16, 2005
PubMed

Insights

Pericardial effusion (PE) is a common complication after acute myocardial infarction (AMI) treated with primary angioplasty, persisting in 38% of cases. Clinical factors like pericardial rub and Killip class > 1 predict persistent PE.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Pericardial effusion (PE) is a known complication following acute myocardial infarction (AMI).
  • Primary percutaneous transluminal coronary angioplasty (PTCA) is a standard reperfusion therapy for AMI.

Purpose of the Study:

  • To determine the incidence of persistent infarct-associated pericardial effusion (PE) after primary angioplasty.
  • To identify clinical factors associated with the persistence of PE post-primary angioplasty.

Main Methods:

  • A consecutive case-series analysis was conducted.
  • 391 patients with AMI undergoing successful primary PTCA were included.
  • Coronary angiography and serial echocardiography were performed to assess coronary flow and PE.

Main Results:

  • PE was present in 19% of patients acutely, associated with higher in-hospital mortality.
  • Of those with acute PE, 38% had persistent PE at 1 month.
  • Pericardial rub, Killip class > 1, and absence of collaterals were significant predictors of persistent PE.

Conclusions:

  • Infarct-associated PE remains a significant complication of AMI despite reperfusion therapy.
  • Clinical indicators such as pericardial rub, elevated Killip class, and lack of collateral flow predict PE persistence.
Abstract

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