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Obstructing tracheal pulmonary Langerhans cell histiocytosis
Zvi G Fridlender1, Mendel Glazer, Gail Amir
1Institute of Pulmonology, Hadassah University Hospital, PO Box 12000, Jerusalem, Israel. Fridlender@hadassah.org.il
Chest
|August 16, 2005
Summary
Pulmonary Langerhans cell histiocytosis, a rare lung disease, can manifest uniquely as a tracheal obstruction. This case highlights a novel presentation and successful treatment via bronchoscopic resection.
Area of Science:
- Pulmonology
- Oncology
- Pathology
Background:
- Pulmonary Langerhans cell histiocytosis (PLCH), also known as eosinophilic granuloma, is an uncommon interstitial lung disease.
- PLCH typically presents with parenchymal nodules, but extralobar or solitary manifestations are rare.
Observation:
- A 55-year-old woman presented with symptoms of tracheal obstruction.
- Imaging revealed a solitary lesion within the trachea.
Findings:
- The tracheal lesion was diagnosed as Langerhans cell histiocytosis.
- Complete resection of the lesion was achieved using flexible bronchoscopy.
Implications:
- This case represents a unique cause of tracheal obstruction due to PLCH.
- It expands the known clinical spectrum of pulmonary Langerhans cell histiocytosis manifestations.