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Updated: Aug 16, 2026

Detection of Infectious Virus from Field-collected Mosquitoes by Vero Cell Culture Assay
Published on: June 9, 2011
Virology, pathology, and clinical manifestations of West Nile virus disease
Edward B Hayes1, James J Sejvar, Sherif R Zaki
1Centers for Disease Control and Prevention, Fort Collins, Colorado 80526, USA. ebh2@cdc.gov
Abstract:
West Nile virus (WNV) causes epidemics of febrile illness, meningitis, encephalitis, and flaccid paralysis. Since it was first detected in New York City in 1999, and through 2004, >16,000 WNV disease cases have been reported in the United States. Over the past 5 years, research on WNV disease has expanded rapidly. This review highlights new information regarding the virology, clinical manifestations, and pathology of WNV disease, which will provide a new platform for further research into diagnosis, treatment, and possible prevention of WNV through vaccination.
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