Related Experiment Video
Updated: Aug 16, 2026
Surgical Technique for Superior Cervical Ganglionectomy in a Murine Model
Published on: December 2, 2022
Surgical management of cervical ganglioneuromas in children
Steven B Cannady1, Brian J Chung, Keiko Hirose
1The Head and Neck Institute, A71, The Cleveland Clinic Foundation, Cleveland, OH, USA.
Objective:
To review the experience with ganglioneuromas in the head and neck of children including presentation, diagnostic testing, treatments, and outcomes.
Design:
Case series. Retrospective chart review.
Setting:
Tertiary care hospital.
Patients Or Other Participants:
All patients with a history of ganglioneuroma of the neck in each authors practice were reviewed. All pathologically confirmed occurrences were eligible for inclusion, and five patients met these criteria.
Results:
Five patients underwent surgical excision of head and neck ganglioneuromas between 1988 and 2004. There were no occurrences of secretory tumors, therefore all of the patients presented with enlarging masses. In all cases, the tumor arose from the cervical sympathetic chain, and thus, patients had subsequent ipsilateral Horner's Syndrome following resection. No synchronous tumors were noted, nor has a recurrent tumor been observed to this point. Complete excision was possible in all cases via a transcervical, or transoral approach, without mandibulotomy.
Conclusions:
Ganglioneuroma of the neck is a rare tumor that most commonly presents as an enlarging neck mass. Complete surgical excision is the treatment of choice, and in this series of children was possible with transcervical approach, and once via transoral approach. This tumor may be suspected in children who are otherwise asymptomatic, and present with long history of enlarging neck masses.
