Calcific retinal embolism as an indicator of severe unrecognised cardiovascular disease

G Ramakrishna1, J F Malouf, B R Younge

  • 1Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA.

Insights

Calcific retinal embolism (CRE) can signal underlying severe heart valve disease, even in asymptomatic patients. Early detection through echocardiography is crucial for identifying this significant cardiovascular risk.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Vascular Medicine

Background:

  • Calcific retinal embolism (CRE) is a rare condition.
  • The association between CRE and cardiac valve stenosis is not well-established.

Purpose of the Study:

  • To describe the association between calcific retinal embolism (CRE) and cardiac valve stenosis.
  • To investigate the prevalence of cardiac valve stenosis in patients with CRE.

Main Methods:

  • Retrospective chart review of patients diagnosed with CRE.
  • Analysis of echocardiography data from 24 patients with CRE.

Main Results:

  • Nine patients (38%) exhibited calcific valve stenosis.
  • Five patients had hemodynamically severe valve stenosis (four aortic, one mitral).
  • Four patients with severe stenosis were asymptomatic.

Conclusions:

  • CRE may be an early indicator of significant, potentially asymptomatic, cardiovascular disease.
  • Severe calcific valve stenosis is a notable underlying condition in patients with CRE.
Abstract

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