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Patch test results from the Mayo Clinic Contact Dermatitis Group, 1998-2000
David A Wetter1, Mark D P Davis, James A Yiannias
1Mayo Clinic Contact Dermatitis Group, Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Journal of the American Academy of Dermatology
|August 23, 2005
Summary
Patch testing effectively identifies allergic contact dermatitis triggers. Mayo Clinic
Area of Science:
- Dermatology
- Allergology
- Contact Dermatitis
Background:
- Patch testing is a crucial diagnostic method for allergic contact dermatitis.
- Mayo Clinic utilizes a standard allergen series, comparable to the North American Contact Dermatitis Group (NACDG).
Purpose of the Study:
- To present patch testing results from Mayo Clinic (July 1998-Dec 2000).
- To compare these findings with concurrent NACDG data.
Main Methods:
- Retrospective analysis of patch test results from 1324 Mayo Clinic patients.
- Comparison of positive reaction rates for common allergens between Mayo Clinic and NACDG.
Main Results:
- 69.3% of patients had at least one positive reaction; 45.8% had two or more.
- Nickel sulfate, balsam of Peru, and neomycin sulfate were among the most frequent allergens.
- Significant differences in reaction rates were noted for 12 of 43 common allergens.
Conclusions:
- Large standard patch test series are effective in identifying common contact allergens.
- This data aids in understanding regional variations in allergen prevalence.