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Nanomanipulation of Single RNA Molecules by Optical Tweezers
Published on: August 20, 2014
Controlled spacing of cationic gold nanoparticles by nanocrown RNA
Alexey Y Koyfman1, Gary Braun, Sergei Magonov
1Department of Chemistry and Biochemistry, University of California - Santa Barbara, 93106-9510, USA.
Journal of the American Chemical Society
|August 25, 2005
Abstract:
Using atomic force microscopy, we describe the linear arrangement of cationic gold nanoparticles directed by programmable self-assembling RNA ladders and demonstrate that the regular spacing of nanoparticles is controlled by the RNA architecture acting as nanocrown scaffoldings. Thus, precise positioning of molecular components can be accomplished with RNA not only through electrostatic but also via size and shape recognitions.
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