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Updated: Aug 16, 2026

Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
Cardiovascular magnetic resonance in the quantitative assessment of left ventricular mass, volumes and contractile
Jonathan C Lyne1, Dudley J Pennell
1Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, UK.
Insights
Cardiovascular magnetic resonance (CMR) accurately assesses heart function, including systolic and diastolic parameters. Ongoing advancements make CMR quicker and easier for clinical and research applications in cardiovascular disease.
Area of Science:
- Cardiovascular Imaging
- Medical Physics
- Cardiac Physiology
Background:
- Cardiovascular magnetic resonance (CMR) is a validated technique for assessing ventricular volumes, function, and mass.
- Current CMR practices evaluate both systolic and diastolic cardiac function.
- CMR offers insights into complex ventricular changes in cardiovascular disease.
Purpose of the Study:
- To review recent developments in cardiovascular magnetic resonance.
- To discuss the current practices of CMR for ventricular assessment.
- To highlight the evolving role of CMR in clinical and research settings.
Main Methods:
- Review of recent advancements in cardiovascular magnetic resonance hardware and software.
- Analysis of current state-of-the-art CMR techniques for ventricular assessment.
- Synthesis of clinical and research applications of CMR.
Main Results:
- CMR is highly accurate and reproducible for assessing ventricular volumes, function, and mass.
- Advanced CMR can evaluate both systolic and diastolic cardiac function.
- Technological refinements are making CMR faster, more accurate, and easier to analyze.
Conclusions:
- Cardiovascular magnetic resonance is a powerful tool for understanding cardiovascular disease.
- Continuous improvements enhance the clinical utility and research value of CMR.
- CMR provides comprehensive insights into cardiac morphology, physiology, and function.
Abstract:
Cardiovascular magnetic resonance is a well validated, highly accurate and reproducible technique for the assessment of ventricular volumes, function and mass. State of the art cardiovascular magnetic resonance practice is capable of a ventricular assessment that includes not only systolic but also diastolic function. Thus, it provides an insight into the complex changes in ventricular morphology, physiology and function in cardiovascular disease. This has produced great interest not only in its clinical utilization but also as an important research tool. As refinement of the technique continues to incorporate hardware and software developments, the technique becomes quicker, more accurate and easier to analyse. Here, we review recent developments and current practice.
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