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Updated: Aug 16, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Enantioselective analysis of an asymmetric reaction using a chiral fluorosensor
Gilbert E Tumambac1, Christian Wolf
1Department of Chemistry, Georgetown University, Washington, D.C. 20057, USA.
Abstract:
An axially chiral 1,8-dipyridylnaphthalene N,N'-dioxide has been employed in enantioselective fluorescence analysis of the enzymatic kinetic resolution of trans-1,2-diaminocyclohexane. The procedure eliminates cumbersome purification and derivatization steps required by traditional methods. The results demonstrate the potential of fluorescence spectroscopy using suitable chiral chemosensors for real-time analysis of the enantiomeric composition of chiral compounds and for high-throughput screening of asymmetric reactions. [structure: see text]
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