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Updated: Aug 16, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Surgical treatment of extravasation injuries
Pietro Napoli1, Bartolo Corradino, Giuseppe Badalamenti
1Chirurgia Plastica e Ricostruttiva, Dipartimento di Discipline Chirurgiche ed Oncologiche, Università degli Studi di Palermo, Italy. pietronapoli@libero.it
Abstract:
The authors present their experience of treating anti-cancer drug extravasation by means of a composite surgical technique that consists of infiltration with physiological solution and hyaluronidase and subsequent manual aspiration of solutes alternated with profuse irrigation of the infiltrated area. In the immediate post-op we carry out a medical therapy that consists of calciparine and topic antibiotic and/or steroid creams. Since the year 2000 this technique has been used on 25 patients. We have had neither complications nor scars.
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