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Critical size defect in the canine mandible
Jin-Young Huh1, Byung-Ho Choi, Byung-Young Kim
1Department of Oral & Maxillofacial Surgery, College of Dentistry, Yonsei University, Seoul, South Korea.
Summary
The critical size defect in canine mandibles is 15 mm without periosteum and 50 mm with periosteum. These findings are crucial for understanding mandibular regeneration and repair.
Area of Science:
- Oral and Maxillofacial Surgery
- Regenerative Medicine
- Veterinary Orthopedics
Background:
- Mandibular defects pose significant challenges in oral and maxillofacial surgery.
- Understanding the critical size defect (CSD) is essential for developing effective regenerative strategies.
Purpose of the Study:
- To determine the CSD in a canine mandible model.
- To evaluate the influence of periosteum preservation on mandibular defect healing.
Main Methods:
- Bilateral mandibular defects were surgically created in 16 adult mongrel dogs.
- Defect sizes ranged from 5 to 60 mm, with and without periosteal resection.
- Radiographic and histologic analyses were performed at 6 months post-surgery.
Main Results:
- Mandibular defects exceeding 15 mm failed to heal when the periosteum was resected.
- Defects larger than 50 mm did not heal when the periosteum was preserved.
Conclusions:
- The CSD in canine mandibles is 15 mm without periosteum and 50 mm with periosteum.
- Periosteal preservation significantly increases the defect size that can spontaneously heal.