[Donor quality of life after living donor liver transplantation]

Júlio Cezar Uili Coelho1, Mônica Beatriz Parolin, Giorgio Alfredo Pedroso Baretta

  • 1Serviço de Transplante hepático do Hospital de Clínicas da Universidade Ferderal do Paraná (HC-UFPR), Curitiba, PR.

Insights

Most living donor liver transplant recipients experienced good recovery and returned to normal activities within months. Postoperative pain was the primary negative aspect reported by donors.

Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Quality of Life Research

Context:

  • Living donor liver transplantation (LDLT) is a critical procedure for end-stage liver disease.
  • Donor quality of life (QoL) after LDLT remains under-evaluated in Brazil.
  • Understanding donor QoL is essential for ethical and sustainable donation practices.

Purpose:

  • To assess the quality of life experienced by living liver donors in Brazil.
  • To identify key factors influencing donor well-being post-transplantation.

Summary:

  • This study evaluated 37 living liver donors in Brazil, with 89% reporting no significant life modifications post-donation.
  • Most donors (57%) returned to regular activities within 3 months, though 59% experienced unanticipated postoperative pain.
  • Financial losses were reported by 57% of donors due to donation-related expenses.

Impact:

  • Findings highlight the generally positive QoL outcomes for living liver donors.
  • Identifies postoperative pain and surgical scarring as significant negative aspects for donors.
  • Provides crucial data for improving donor care and support in Brazil.
Abstract

Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...