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Updated: Aug 11, 2026

Technique of Subnormothermic Ex Vivo Liver Perfusion for the Storage, Assessment, and Repair of Marginal Liver Grafts
Published on: August 13, 2014
[Donor quality of life after living donor liver transplantation]
Júlio Cezar Uili Coelho1, Mônica Beatriz Parolin, Giorgio Alfredo Pedroso Baretta
1Serviço de Transplante hepático do Hospital de Clínicas da Universidade Ferderal do Paraná (HC-UFPR), Curitiba, PR.
Insights
Most living donor liver transplant recipients experienced good recovery and returned to normal activities within months. Postoperative pain was the primary negative aspect reported by donors.
Area of Science:
- Hepatology
- Transplantation Surgery
- Quality of Life Research
Context:
- Living donor liver transplantation (LDLT) is a critical procedure for end-stage liver disease.
- Donor quality of life (QoL) after LDLT remains under-evaluated in Brazil.
- Understanding donor QoL is essential for ethical and sustainable donation practices.
Purpose:
- To assess the quality of life experienced by living liver donors in Brazil.
- To identify key factors influencing donor well-being post-transplantation.
Summary:
- This study evaluated 37 living liver donors in Brazil, with 89% reporting no significant life modifications post-donation.
- Most donors (57%) returned to regular activities within 3 months, though 59% experienced unanticipated postoperative pain.
- Financial losses were reported by 57% of donors due to donation-related expenses.
Impact:
- Findings highlight the generally positive QoL outcomes for living liver donors.
- Identifies postoperative pain and surgical scarring as significant negative aspects for donors.
- Provides crucial data for improving donor care and support in Brazil.
Background:
Quality of life of the donor after living donor liver transplantation has not been evaluated in Brazil yet.
Aim:
To evaluate the quality of live of the donor after living donor liver transplantation.
Methods:
Of a total of 300 liver transplantations, 51 were of living donors. All donors with less than 6 months of follow-up and those who did not want to participate were excluded from the study. The donors answered a questionnaire contained 28 questions about several aspects of donation. Demographic and clinical data from the donors were also evaluated.
Results:
Thirty-seven donors were included in the study. Thirty-two were first or second degree relatives of the receptor. Only one donor would not donate again. Twenty-two donors (59%) experienced more postoperative pain than they had previously anticipated. Return to regular activities occurred in less than 3 months for 21 donors (57%). Twenty-one donors (57%) referred financial loss with the donation due to expenses with medications, exams, transportation or lost wages. Thirty-three (89%) had no modification or limitation in their lives after donation. The most negative aspects of donation were postoperative pain and the presence of a surgical scar. Most postoperative complications resolved with clinical treatment, but severe or potentially fatal complications occurred in two patients.
Conclusions:
Most donors had good recovery and returned to regular activities few months after donation. The most negative aspect of donation was postoperative pain.
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