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Related Experiment Videos

Chlorhexidine gluconate.

Bettina Basrani1, Carlie Lemonie

  • 1Faculty of Dentistry, University of Toronto, 124 Edward Street #348C, M5SG 1G6. Toronto, Ontario, Canada. Bettina.basrani@utoronto.ca

Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc
|September 1, 2005
PubMed
Summary

Chlorhexidine gluconate (CHX) offers comparable antibacterial efficacy to sodium hypochlorite (NaOCI) for root canal treatment, with lower toxicity and potential for residual antimicrobial effects. This review details CHX

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Area of Science:

  • Endodontics
  • Microbiology
  • Dental Materials Science

Background:

  • Root canal treatment aims to eradicate bacteria and prevent reinfection.
  • Despite biomechanical cleaning, complex root canal anatomy harbors residual bacteria and debris.
  • Effective intracanal irrigants are crucial for removing contaminants and the smear layer.

Purpose of the Study:

  • To review the properties and applications of Chlorhexidine gluconate (CHX) as a root canal irrigant.
  • To compare the efficacy and toxicity of CHX with Sodium Hypochlorite (NaOCI).

Main Methods:

  • Literature review focusing on studies evaluating CHX in endodontic treatment.
  • Analysis of antibacterial efficacy, tissue-dissolving properties, and toxicity profiles.
  • Examination of residual antimicrobial activity and dentine surface interactions.

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Main Results:

  • CHX demonstrates broad-spectrum antimicrobial activity, effective against resistant strains.
  • Its antibacterial efficacy is comparable to NaOCI, a common irrigant.
  • CHX exhibits lower toxicity than NaOCI and may provide residual antimicrobial effects on dentine.

Conclusions:

  • CHX is a viable alternative irrigant and intracanal medicament in endodontics.
  • Its comparable efficacy, lower toxicity, and residual activity warrant further consideration.
  • CHX presents a promising option for enhancing root canal disinfection protocols.