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Gastric extramedullary plasmacytoma in a dog
S R Brunnert1, L A Dee, A J Herron
1Department of Pathology, School of Medicine, University of Miami, FL 33101.
Summary
A rare gastric plasmacytoma in a dog was successfully treated with surgery and chemotherapy, leading to long-term survival. This suggests better outcomes for this specific canine stomach cancer compared to other gastric tumors.
Area of Science:
- Veterinary Oncology
- Canine Pathology
Background:
- Gastric plasmacytomas are uncommon neoplasms in dogs.
- Vomiting and diarrhea are common clinical signs of gastric disease in canines.
Observation:
- A 10-year-old dog presented with a 6-week history of daily vomiting and diarrhea.
- Gastroscopy revealed a crateriform mass on the stomach's greater curvature.
- A large mesenteric lymph node was also noted.
Findings:
- Surgical resection (partial gastrectomy and lymphadenectomy) was performed.
- Histologic and immunoperoxidase diagnoses confirmed gastric plasmacytoma with lymph node metastasis.
- Chemotherapy with doxorubicin and diphenhydramine was initiated.
Implications:
- Long-term survival (30+ months) was achieved in this case.
- Gastric plasmacytoma may have a more favorable prognosis in dogs than other gastric malignancies.
- This case highlights the importance of early diagnosis and multimodal treatment for canine gastric tumors.