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Sol-gel-coated oligomers as novel stationary phases for solid-phase microextraction
Chanbasha Basheer1, Subbiah Jegadesan, Suresh Valiyaveettil
1Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Singapore.
Journal of Chromatography. A
|September 1, 2005
Summary
New sol-gel coatings on fused silica capillaries offer efficient solid-phase microextraction for diverse analytes. These stable, high-temperature coatings provide sensitive and selective preconcentration, comparable to commercial options.
Area of Science:
- Analytical Chemistry
- Materials Science
- Environmental Science
Background:
- Solid-phase microextraction (SPME) is a vital technique for sample preparation.
- Developing novel, stable, and efficient SPME coatings is crucial for trace analyte determination.
- Existing SPME materials may have limitations in handling diverse analyte polarities or thermal stability.
Purpose of the Study:
- To synthesize and evaluate novel amphiphilic and hydrophilic oligomer-based sol-gel coatings for fused silica capillaries.
- To assess the performance of these sol-gel coatings for solid-phase microextraction (SPME) and preconcentration of various non-polar and polar analytes.
- To compare the extraction efficiency, selectivity, and sensitivity of the new coatings with commercially available SPME adsorbents.
Main Methods:
- Synthesis of amphiphilic and hydrophilic oligomers.
- Coating of fused silica capillaries using a sol-gel technique.
- Evaluation of coating stability at high temperatures (up to 280°C).
- Assessment of extraction efficiency for organochlorine pesticides, triazine herbicides, estrogens, alkylphenols (APs), and bisphenol-A (BPA).
- Comparison with commercial SPME adsorbents (e.g., poly(dimethylsiloxane)-divenylbenzene, polyacrylate).
- Determination of linearity, detection limits, and precision for target analytes.
- Application in the analysis of triazine herbicides in reservoir water samples.
Main Results:
- Sol-gel coatings exhibited excellent thermal stability up to 280°C.
- Both amphiphilic and hydrophilic coatings demonstrated effective extraction of a wide range of non-polar and polar analytes.
- The new sol-gel SPME materials showed comparable selectivity and sensitivity to commercial adsorbents.
- Good linearity and low detection limits were achieved, with an example of <0.005 µg/L for triazines.
- The method was successfully applied to determine triazine herbicides in real water samples.
Conclusions:
- Sol-gel coated capillaries represent a promising alternative for SPME applications.
- The developed coatings offer robust performance for the preconcentration of diverse analytes.
- These novel materials provide a viable option for sensitive and selective trace analysis in environmental monitoring.