Related Experiment Video
Updated: Jul 12, 2026
13:44
Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
Published on: August 30, 2013
Planar chiral cyclic ether: asymmetric resolution and chirality transformation
Katsuhiko Tomooka1, Nobuyuki Komine, Daisuke Fujiki
1Department of Applied Chemistry, Graduate School of Science and Engineering, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8552, Japan. ktomooka@apc.titech.ac.jp
Journal of the American Chemical Society
|September 1, 2005
Summary
Stable planar chirality was discovered in a nine-membered cyclic ether. This novel chiral building block was synthesized using kinetic resolution, yielding an enantiomerically enriched compound.
Area of Science:
- Organic Chemistry
- Stereochemistry
Background:
- Planar chirality is a type of chirality where chirality arises from the arrangement of substituents around a plane.
- Cyclic ethers are versatile compounds with applications in various chemical syntheses.
Purpose of the Study:
- To investigate the synthesis and properties of a novel nine-membered diallylic cyclic ether.
- To explore the potential of this compound as a chiral building block.
Main Methods:
- Kinetic resolution of a racemic mixture of the cyclic ether.
- Characterization of the enantiomerically enriched product.
Main Results:
- Remarkably stable planar chirality was observed in the nine-membered diallylic cyclic ether.
- Enantiomerically enriched ether was successfully prepared via kinetic resolution.
Conclusions:
- The synthesized nine-membered diallylic cyclic ether exhibits stable planar chirality.
- This compound represents a valuable new chiral building block for organic synthesis.
Related Concept Videos
01:15Properties of Laplace Transform-I
The Laplace transform is a powerful mathematical tool used to convert functions from the time domain into the frequency domain, greatly simplifying the analysis and solution of linear time-invariant systems. This transformation is facilitated by several universal properties: Linearity, Time-Scaling, Time-Shifting, and Frequency Shifting.
The Linearity property is foundational to the Laplace transform. It states that the transform of a linear combination of functions is equivalent to the same...
The Linearity property is foundational to the Laplace transform. It states that the transform of a linear combination of functions is equivalent to the same...
01:18Aliasing
Accurate signal sampling and reconstruction are crucial in various signal-processing applications. A time-domain signal's spectrum can be revealed using its Fourier transform. When this signal is sampled at a specific frequency, it results in multiple scaled replicas of the original spectrum in the frequency domain. The spacing of these replicas is determined by the sampling frequency.
If the sampling frequency is below the Nyquist rate, these replicas overlap, preventing the original signal...
If the sampling frequency is below the Nyquist rate, these replicas overlap, preventing the original signal...
01:29Transformations of Functions I
A function's graph can be modified by changing its position or size without altering its overall shape. These transformations allow the graph to be moved across the coordinate plane while preserving its pattern and structure. One of the most common transformations is shifting, which repositions the graph without distorting it.When the output of a function is adjusted by adding or subtracting a constant, the graph shifts vertically. A positive value moves the graph upward, while a negative value...
01:24Polar Coordinates
The polar coordinate system offers an alternative to the Cartesian coordinate system for specifying points in a plane, using a distance and an angle instead of x and y coordinates. This system is particularly advantageous in situations involving circular or rotational symmetry, such as in physics or engineering problems involving waves, oscillations, or orbital paths.Defining Polar CoordinatesIn polar coordinates, a point is represented as P(r, ��), where r is the radial distance from a fixed...
01:29Transformations of Functions II
Transformations in mathematics alter the position or orientation of a function’s graph while preserving its fundamental shape. One important type of transformation is the horizontal shift, which involves modifying the input variable within a function’s equation. This operation affects where outputs occur along the horizontal axis but does not alter the function’s overall structure.A horizontal shift is achieved by replacing the input variable x with either x + c or x - c, where c is a constant.
01:20Transformations of Functions III
Transformations modify the graphical representation of a function without changing its fundamental form. One common transformation is reflection, which flips the graph across a designated axis. When the vertical coordinates of all points are multiplied by the negative one, the entire graph is mirrored over the horizontal axis. This transformation reverses the vertical orientation of peaks and troughs, akin to signal inversion in electrical systems, where a waveform is flipped, but the timing of...