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The old-old-old.

Knight Steel1

  • 1University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ, USA. ksteel@humed.com

Journal of the American Geriatrics Society
|September 1, 2005
PubMed
Summary
This summary is machine-generated.

Distinguishing aging from disease is challenging, especially when considering environmental factors. Manipulating the aging process may further blur the lines between normal aging and illness, impacting future health outcomes.

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Area of Science:

  • Gerontology
  • Pathology
  • Environmental Health

Background:

  • Geriatricians differentiate aging from disease.
  • Separating aging, disease, and environmental effects is complex.
  • The potential to manipulate the aging process raises new questions.

Purpose of the Study:

  • To explore the challenges in distinguishing aging from disease.
  • To speculate on the future appearance of elders if aging is manipulated.
  • To consider the implications of altering aging on organ systems and disease onset.

Main Methods:

  • Conceptual analysis of aging and disease processes.
  • Speculative modeling of future aging scenarios.
  • Discussion of the impact of environmental factors on aging and disease.

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Main Results:

  • The distinction between aging and disease is difficult to maintain.
  • Environmental factors significantly influence both aging and disease.
  • Manipulating aging may alter organ-specific effects and disease timelines.

Conclusions:

  • The separation of aging, disease, and environmental influences is challenging.
  • Future interventions in aging may redefine our understanding of health and disease.
  • The onset of disease may be better understood in relation to lifespan rather than from birth.