Related Experiment Video
Updated: Aug 16, 2026
Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node
H Hayashi1, T Ochiai, H Shimada
1Research Center for Frontier Medical Engineering, 1-33, Yayoi-cho, Inage-ku, Chiba, 263-8522, Japan. hhayashi@faculty.chiba-u.jp
Background:
Laparoscopy-assisted surgery with extraperigastric lymph node dissection for gastric cancers has been described, but the clinical benefits of these surgeries still are unclear. Short-term clinical outcomes were compared between laparoscopy-assisted distal gastrectomy (LADG) and conventional open distal gastrectomy (ODG) for early gastric cancer in a prospective randomized fashion.
Methods:
For this study, 28 patients with early gastric cancers in the lower half of the stomach were randomly assigned to either LADG (n = 4) or ODG (n = 14). Postoperative pain, levels of acute inflammatory responses, and pathologic evaluation of the operative specimens were compared.
Results:
The LADG group required a significantly shorter period of postoperative epidural anesthesia, showed significantly lower levels of serum interleukin-6 and C-reactive protein, and had no major postsurgery complications. Pathologic examinations showed that surgery was equally radical in the two groups.
Conclusion:
The findings show that LADG with extraperigastric lymph node dissection is a safe and less invasive alternative to the open procedure.
