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Prenatal three-dimensional/four-dimensional sonographic demonstration of facial dysmorphisms associated with
Chih-Ping Chen1, Jin-Chung Shih, Chin-Yuan Hsu
1Department of Obstetrics and Gynecology, Mackay Memorial Hospital, 92 Section 2, Chung-Shan North Road, Taipei, Taiwan, Republic of China.
Abstract:
In this report, we describe the prenatal use of 3-dimensional 4-dimensional (3D/4D) sonography to visualize the facial dysmorphisms associated with holoprosencephaly in 6 fetuses (2 with cyclopia, 1 with cebocephaly, and 3 with holoprosencephaly-premaxillary agenesis). Ultrafast MRI was also used. The 3D/4D sonographic images allowed easy, rapid, and precise prenatal evaluation of the facial dysmorphisms associated with holoprosencephaly; the MRI scans provided little additional information. The 3D/4D sonograms helped the parents visualize the abnormalities and facilitated their acceptance of perinatal genetic counseling.
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