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Updated: Aug 16, 2026

An Optimized Protocol for Electrophoretic Mobility Shift Assay Using Infrared Fluorescent Dye-labeled Oligonucleotides
Published on: November 29, 2016
[New advances in Sox gene family]
Zhong-jie Chang1, Qi-yan Du, Hong-wei Shao
1College of life sciences, Henan Normal University, Xinxiang city,453002, China. zhjch@public.xxptt.ha.cn
Abstract:
The Sox family of transcription factors are found throughout the animal kingdom. They are characterized by the presence of a HMG domain, involved in the regulation of such diverse developmental processes of early embryogenesis as sex determination,chondrogenesis,haemopoiesis,neural development and lens development. The deletion or mutation of SOX proteins results in developmental defects and congential disease in human. One Sox gene has different effects on the same promoters in the different cells or the different promoters in a cell. Some Sox gene exhibit a remarkable crosstalk and functional redundancy among each other. This paper reviewed the advances related to the Sox gene family in recent years.
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