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Pulsatile tinnitus in a 16-year-old patient
Yoshimi Sogawa1, Richard Libman, Lydia Eviatar
1Division of Pediatric Neurology, Schneider Children's Hospital, New Hyde Park, New York 11040, USA.
Pediatric Neurology
|September 6, 2005
Summary
A child
Area of Science:
- Neurology
- Genetics
- Pediatrics
Background:
- Pulsatile tinnitus can indicate serious underlying neurological conditions.
- Cerebral venous thrombosis (CVT) is a rare but significant cause of intracranial hypertension in children.
Observation:
- A pediatric case presenting with pulsatile tinnitus.
- Investigated for potential causes of increased intracranial pressure.
Findings:
- The child exhibited pulsatile tinnitus attributed to increased intracranial hypertension.
- Cerebral venous thrombosis was identified as the likely cause.
- Genetic analysis revealed homozygosity for the prothrombin gene G20210A mutation and heterozygosity for the factor V Leiden mutation.
Implications:
- Highlights the importance of investigating pulsatile tinnitus and intracranial hypertension in pediatric patients.
- Identifies specific genetic thrombophilias (prothrombin G20210A, factor V Leiden) as potential risk factors.
- Emphasizes the need for prompt diagnosis and management of CVT to prevent severe neurological sequelae.