PISA method for assessment of mitral regurgitation in children

Osman Başpinar1, Sevim Karaaslan, Bülent Oran

  • 1Department of Pediatric Cardiology, Gaziantep University Faculty of Medicine, 27310 Gaziantep, Turkey. osmanbaspinar@hotmail.com

Insights

The proximal isovelocity surface area (PISA) method accurately assesses rheumatic mitral regurgitation (MR) in children. This echocardiographic technique provides reliable measurements comparable to Doppler methods for evaluating MR severity.

Area of Science:

  • Pediatric Cardiology
  • Echocardiography
  • Valvular Heart Disease

Background:

  • Rheumatic mitral regurgitation (MR) is a significant cause of heart disease in children.
  • Accurate assessment of MR severity is crucial for timely intervention and management.
  • Echocardiographic methods are essential for evaluating MR in pediatric populations.

Purpose of the Study:

  • To evaluate the feasibility and clinical significance of the proximal isovelocity surface area (PISA) method for assessing rheumatic mitral regurgitation (MR) in children.
  • To compare PISA-derived measurements with traditional echocardiographic techniques in pediatric MR patients.

Main Methods:

  • Thirty-one children with chronic MR underwent evaluation using semiquantitative and quantitative Doppler, 2D echocardiography, and the PISA method.
  • Effective regurgitant orifice area, regurgitation volume, and left ventricular systolic function were compared between mild-moderate and severe MR groups.
  • Correlation analyses were performed between PISA parameters and other echocardiographic indices.

Main Results:

  • PISA method showed no statistically significant differences in regurgitant orifice area and volume compared to quantitative Doppler (p>0.05).
  • Excellent correlations were observed between PISA-derived regurgitant orifice area/volume and the radius of the proximal flow convergence hemisphere (r=0.882-0.925, p<0.05).
  • Good correlations were found between PISA-derived regurgitant orifice area and left ventricular end-diastolic diameter, jet/atrial area ratio, and color Doppler grading (r=0.618-0.763, p<0.05).

Conclusions:

  • The proximal isovelocity surface area (PISA) method is a feasible and accurate tool for predicting mitral regurgitation (MR) in children.
  • PISA measurements correlate well with established Doppler methods, offering a reliable alternative for MR assessment in pediatric patients.
  • This study supports the use of PISA as a valuable echocardiographic technique in the management of pediatric rheumatic heart disease.
Abstract

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