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Sensitization to common allergens in adults with asthma
Felicia Allen-Ramey1, William F Schoenwetter, Thomas W Weiss
1Outcomes Research and Management, Merck & Co., Inc., West Point, PA 19486, USA.
The Journal of the American Board of Family Practice
|September 9, 2005
Summary
Most adult asthma patients have atopy, or allergen sensitization. Identifying specific allergen sensitivities in these patients can improve asthma management and patient outcomes.
Area of Science:
- Allergy and Immunology
- Pulmonology
- Clinical Medicine
Background:
- Atopy, or allergen sensitization, is a common condition.
- Asthma is a chronic respiratory disease often linked to allergic triggers.
Purpose of the Study:
- To determine the prevalence of atopy in adult asthma outpatients.
- To identify specific allergen sensitivities in this population.
Main Methods:
- A cohort of 218 adult asthma patients (18-55 years) was studied.
- Blood samples were analyzed for total and specific IgE levels against 8 common allergens.
- Physicians specializing in Family Practice, Allergy, or Pulmonology participated.
Main Results:
- 68% of asthma patients met the definition of atopy.
- 48% had elevated total serum IgE levels.
- 59% showed elevated specific IgE to at least one common allergen.
Conclusions:
- The majority of adult asthma outpatients exhibit atopy.
- Most patients are sensitive to identifiable allergens.
- Recognizing high atopy prevalence can enhance asthma patient care.