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Nail discoloration induced by doxycycline
Mustafa Akcam1, Reha Artan, Fusun Zeynep Akcam
1Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Medical School, Akdeniz University, Antalya, Turkey. makcam88@hotmail.com
The Pediatric Infectious Disease Journal
|September 9, 2005
Summary
Doxycycline, a common antibiotic, can rarely cause nail discoloration in children. This case highlights a rare side effect of doxycycline in pediatric patients, emphasizing the need for awareness among healthcare providers.
Area of Science:
- Pharmacology
- Pediatric Medicine
- Dermatology
Background:
- Tetracyclines, including doxycycline, are known to deposit in calcifying tissues like bone and teeth.
- Hyperpigmentation of skin, teeth, and nails is a documented side effect of tetracycline use.
Observation:
- Nail discoloration is a rarely reported adverse effect of doxycycline in pediatric populations.
- This case presents an 11-year-old boy experiencing nail discoloration attributed to doxycycline intake.
Findings:
- The study documents a rare instance of nail discoloration in a pediatric patient following doxycycline administration.
- This finding contributes to the limited literature on doxycycline-induced nail hyperpigmentation in children.
Implications:
- Healthcare providers should be aware of the potential for rare nail discoloration as a side effect of doxycycline in pediatric patients.
- This case underscores the importance of monitoring for and reporting unusual adverse drug reactions in children.