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Two-dimensional acoustic pattern derived strain parameters closely correlate with one-dimensional tissue Doppler
Karen M Modesto1, Sanderson Cauduro, Angela Dispenzieri
1Division of Cardiology, Mayo Clinic College of Medicine, Rochester, MN, USA.
Summary
Two-dimensional strain echocardiography (2D-SE) provides reliable cardiac strain measurements comparable to tissue Doppler-derived strain echocardiography (TD-SE). This validated 2D-SE method can aid in routine clinical deformation analysis.
Area of Science:
- Cardiology
- Medical Imaging
- Echocardiography
Background:
- Two-dimensional strain echocardiography (2D-SE) tracks tissue velocities for 2D strain parameters.
- Novel software enhances 2D-SE with semi-automated measurements and improved signal-noise ratio.
Purpose of the Study:
- To compare the clinical utility of 2D-SE with validated tissue Doppler-derived strain echocardiography (TD-SE).
Main Methods:
- 2D-SE and TD-SE were performed on 17 patients with amyloid cardiomyopathy and 10 healthy volunteers.
- Longitudinal strain rate and strain were analyzed from standard apical views at high frame rates.
- Offline analysis was conducted by blinded observers using EchoPAC software.
Main Results:
- Acceptable strain data quality was achieved in 92% (2D-SE) and 85% (TD-SE) of segments.
- 2D-SE and TD-SE values showed close correlation for strain rate (r=0.94) and strain (r=0.96).
Conclusions:
- 2D-SE is feasible for clinical deformation analysis, yielding results comparable to TD-SE.
- 2D-SE measurements correlate well with TD-SE across a broad spectrum of systolic function.
- 2D-SE has the potential to facilitate routine clinical implementation of deformation analysis.