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Lemierre syndrome.

Myto Duong1, Jodi Wenger

  • 1Department of Pediatrics, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA. mduong@slu.edu

Pediatric Emergency Care
|September 15, 2005
PubMed
Summary
This summary is machine-generated.

Lemierre syndrome, a serious infection involving throat inflammation and Fusobacterium necrobacillosis sepsis, is increasingly reported. This case highlights the importance of recognizing and treating this potentially fatal condition, characterized by internal jugular vein thrombosis and abscesses.

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Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Vascular Surgery

Background:

  • Lemierre syndrome, often termed 'the forgotten fever,' is a rare but severe condition typically following pharyngitis.
  • It involves Fusobacterium necrophorum sepsis, internal jugular vein thrombosis, and distant abscess formation.
  • Recent years have seen an increase in reported cases, necessitating greater awareness.

Observation:

  • A case study of a 17-year-old female with Lemierre syndrome is presented.
  • The patient experienced typical symptoms including sore throat, fever, and neck swelling.
  • Diagnostic imaging confirmed internal jugular vein thrombosis and metastatic abscesses.

Findings:

  • Fusobacterium necrophorum was identified as the causative agent.

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  • The pathophysiology involves bacterial translocation from the pharynx to the bloodstream, leading to septic thrombophlebitis.
  • Early diagnosis and prompt antibiotic therapy are crucial for favorable outcomes.

    • Implications:

    • Increased recognition of Lemierre syndrome is vital for timely diagnosis and management.
    • Understanding the pathophysiology aids in developing targeted treatment strategies.
    • This case underscores the need for vigilance in patients presenting with severe pharyngitis and associated complications.