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Treatment options for cyclic vomiting syndrome.
1Division of Gastroenterology, Hepatology, and Nutrition, Children's Memorial Hospital, #57, 2300 Children's Plaza, Chicago, IL 60614, USA.
Current Treatment Options in Gastroenterology
|September 16, 2005
Summary
Cyclic vomiting syndrome (CVS) treatment is evolving, incorporating lifestyle changes and various medications. Current approaches focus on preventing episodes, managing acute attacks, and providing family support for better outcomes.
Area of Science:
- Gastroenterology
- Neurology
Background:
- Idiopathic cyclic vomiting syndrome (CVS) lacks clear pathogenesis and controlled trials, leading to empiric treatment.
- Treatment strategies for CVS have historically been limited due to these challenges.
Purpose of the Study:
- To update the treatment approach for cyclic vomiting syndrome (CVS).
- To review current evidence and guidelines for managing CVS.
Main Methods:
- Review of open-label trials and retrospective case series.
- Incorporation of upcoming consensus guidelines for CVS management.
Main Results:
- A comprehensive treatment approach includes lifestyle modifications, trigger avoidance, and pharmacotherapy.
- Medications such as antimigraine, anti-emetic, and anticonvulsive agents show 40-90% efficacy for prophylaxis and acute episodes.
- Triptans are effective for aborting episodes, while antiemetics and sedatives manage acute symptoms.
Conclusions:
- Current CVS treatment integrates lifestyle adjustments and pharmacologic interventions.
- Multifaceted treatment strategies are essential for managing cyclic vomiting syndrome effectively.
- Further research and consensus guidelines will refine CVS therapeutic approaches.