Related Experiment Video
Updated: Aug 15, 2026
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
Published on: July 3, 2025
The use of fluor-hydroxy pulse peel in actinic porokeratosis
Solange P Teixeira1, Maurício M de Nascimento, Ediléia Bagatin
1Department of Dermatologym Cosmiatry Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil. solangeteixeira@clinderm.com.br
Background:
The use of Fluor-Hydroxy pulse peel (Drogaderma, Sao Paulo, Brazil) was reported by Katz to treat solar damage and actinic keratosis-associated lesions.
Objective:
The objective was to use this combined treatment to produce therapeutic and cosmetic benefits in a patient with actinic porokeratosis.
Methods:
A case of actinic disseminated porokeratosis was treated with a combination of a 70% glycolic peel and a 5% 5-fluorouracil solution (Drogaderma) every 2 weeks for 4 months. A biopsy was done before and after eight treatment pulses.
Results:
Improvement in the appearance and texture of the treated areas and decreased dyskeratosis and epidermal atypia.
Conclusion:
The Fluor-Hydroxy pulse peel can be an effective alternative for the treatment of actinic porokeratosis.
