Indications for allografts

Allografts continue to be popular in orthopaedic reconstruction procedures of the knee. Approximately 1 million musculoskeletal allografts were distributed in the United States in 2004 alone. Ligament allografts, osteochondral allografts, and meniscal transplants have all demonstrated success in knee reconstructions. The advantages of allograft tissue include the lack of donor site morbidity, shorter operative times, ease of sizing, and a lack of clinically significant immunologic reactions. These advantages should be weighed against the risk for disease transmission, increased cost, and increased time of graft incorporation. Throughout the consent process, comprehensive patient education is imperative to assist in this important decision.