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FDG-PET imaging in Pneumocystis carinii pneumonia

Zarni Win1, Jonathan Todd, Adil Al-Nahhas

  • 1Department of Nuclear Medicine, Hammersmith Hospital, London, UK. zarni_win@hotmail.com

Clinical Nuclear Medicine
|September 17, 2005
PubMed

Insights

A case study highlights Pneumocystis pneumonia (PCP) in an immunocompromised patient. F-18 fluorodeoxyglucose positron emission tomography (FDG PET) effectively monitored treatment response, showing complete resolution of lung changes.

Area of Science:

  • Medical Imaging
  • Infectious Diseases
  • Pulmonology

Background:

  • Presents a case of a 26-year-old male investigated for Cushing syndrome.
  • Patient exhibited acute symptoms of dry cough and fever with leukopenia.

Observation:

  • Imaging suggested atypical pneumonia, confirmed as Pneumocystis carinii pneumonia (PCP) via bronchoalveolar lavage (BAL) cytology.
  • Acute lung changes were visualized using whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET).

Findings:

  • FDG PET imaging successfully demonstrated acute lung changes associated with PCP.
  • Follow-up FDG PET studies after treatment showed complete resolution of these pulmonary abnormalities.

Implications:

  • Suggests a potential diagnostic and monitoring role for FDG PET in PCP.
  • Highlights FDG PET's utility in assessing treatment efficacy for PCP in immunocompromised individuals.

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