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Isolated left main coronary stenosis and mediastinal irradiation
B R Chinnasami1, R C Schwartz, S B Pink
1Department of Medicine, Polyclinic Medical Center, Harrisburg, Pennsylvania 17110.
Clinical Cardiology
|June 1, 1992
Abstract:
This report draws an association between mediastinal irradiation and isolated left main coronary artery stenosis. The report highlights two patients who developed selective left main coronary artery stenosis post mediastinal treatment. In the animal model, it has been shown that high serum cholesterol levels at the time of, or soon after, irradiation are necessary to initiate arteriosclerotic plaque formation.